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  U.S. Department of Health and Human Services | National Institutes of Health

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  • Created by Pauly, Kelly (NIH/OD) [E], last modified on Mar 27, 2024

NIH as Participating Site Relying on an External IRB (sIRB)


Guideline-NIH Study Team- when Relying on an External IRB 04.06.2023.pdf295 kB

Relying on WCG IRB (formerly WIRB)

Guideline - WCG for Researchers 01.19.2024.pdf956 kB
Presentation - NIH Investigators seeking to use the Western IRB (WIRB) 08.06.2019.pptx1.74 MB
Presentation - WCG for Investigators.pptx1.19 MB


Guidance - Using NIH funds to Pay for Advarra or WCG IRB Services.pdf 

Video - WIRB Orientation for Investigators and Research Team


Relying on Advarra

ADVARRA IRB Handbook 09.05.2021.pdf921 kB
Presentation - Advarra for Investigators 07.30.2019.pptx2.67 MB
Presentation - NIH Investigators seeking to use the Advarra IRB.pdf307 kB
Using Advarra IRB- Informational Session 09.20.2020.mp467.24 MB


Guidance - Using NIH funds to Pay for Advarra or WCG IRB Services.pdf 

Video - Advarra Orientation for Investigators and Research Team


Submitting in PROTECT

  • Presentation-Tips &  Tricks: Preparing Submissions When Relying on an External IRB 01.03.2024
  • PROTECT Tip Sheet for NIH Research Teams: Tips and Tricks: Relying on a External IRB
  • Find Step by Step PROTECT Multi-site Guides in the PROTECT Help Center


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